Ethyl p-(piperidinoacetylamino)benzoate - Names and Identifiers
Name | Ethyl piperidinoacetylaminobenzoate
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Synonyms | SA-7 Sulcain Sulcaine Nichicaine BRN 1292603 UNII-6M452G7O1F Ethyl piperidylacetylaminobenzoate ethyl piperidinoacetylaminobenzoate Ethyl piperidinoacetylaminobenzoate Ethyl p-(piperidinoacetylamino)benzoate Ethyl piperidinoacetylaminobenzoate [JAN] 5-20-03-00024 (Beilstein Handbook Reference) ethyl 2-[(piperidin-1-ylacetyl)amino]benzoate p-(Piperidinoacetamide)benzoic acid ethyl ester p-(2-Piperidinoacetamido)benzoic acid ethyl ester 4-[(Piperidinoacetyl)amino]benzoic acid ethyl ester p-(2-Piperidinoacetylamino)benzoic acid ethyl ester Benzoic acid, p-(2-piperidinoacetamido)-, ethyl ester 4-[(1-Piperidinylacetyl)amino]benzoic acid ethyl ester Benzoic acid, 4-[[2-(1-piperidinyl)acetyl]amino]-, ethyl ester
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CAS | 41653-21-8
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InChI | InChI=1/C16H22N2O3/c1-2-21-16(20)13-8-4-5-9-14(13)17-15(19)12-18-10-6-3-7-11-18/h4-5,8-9H,2-3,6-7,10-12H2,1H3,(H,17,19) |
Ethyl p-(piperidinoacetylamino)benzoate - Physico-chemical Properties
Molecular Formula | C16H22N2O3
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Molar Mass | 290.36 |
Density | 1.159g/cm3 |
Boling Point | 468.885°C at 760 mmHg |
Flash Point | 237.374°C |
Vapor Presure | 0mmHg at 25°C |
Refractive Index | 1.565 |
Ethyl p-(piperidinoacetylamino)benzoate - Introduction
Ethyl piperidinoacetylaminobenzoate, also known chemically as acetamide ethyl benzoate, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystal or crystalline powder
-Molecular formula: C17H23NO3
-Molecular weight: 289.37g/mol
-Solubility: Soluble in polar organic solvents such as alcohols, ethers and chlorinated hydrocarbons, insoluble in water
-Melting point: approximately 72-74°C
Use:
- Ethyl piperidinoacetylaminobenzoate is an organic synthesis intermediate commonly used in the synthesis of drugs and biologically active molecules.
-It is often used as a chiral reagent in the field of pharmaceutical research, such as the synthesis of chiral compounds.
-In addition, it can also be used to synthesize and study biologically active compounds.
Preparation Method:
Ethyl piperidinoacetylaminobenzoate can be synthesized by the following steps:
1. the first piperidine dissolved in alcohol solvent.
2. Add acetic acid and benzoic acid for esterification.
3. Add acetyl chloride for acylation.
4. Finally, the product was washed with ethanol, isolated and dried to give Ethyl piperidinoacetylaminobenzoate.
Safety Information:
- Ethyl piperidinoacetylaminobenzoate is stable at room temperature, but should be kept away from fire and oxidant.
-Wear appropriate protective equipment such as gloves and glasses during operation.
-Avoid inhalation or contact with skin and eyes.
-Store in a sealed container, away from fire and high temperature.
-For unintended contact or ingestion, seek prompt medical attention.
Last Update:2024-04-09 21:00:56